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Settles Lab

Settles Lab

Lab Members

Headshot photo of Dr. Mark Settles

Dr. A. Mark Settles
Principal Investigator

Dr. A. Mark Settles was a Vasil-Monsanto professor of Plant Cell and Molecular Biology in the Horticultural Sciences Department at the University of Florida. Recently, Dr. Settles accepted a new position at NASA AMES Research Center as Synthetic Biology Lead Investigator! Subsequently, he was awarded the status of Emeritus Professor here at UF. 

While at UF, his research focused primarily on genes that influence the growth and development of corn seeds, though he is also interested in machine vision learning research and growing algae in space for bioregenerative life support systems.

His most recent research at UF bridges cell and developmental biology to applied plant breeding and space biology. The unifying scientific theme of his work has been studying the cereal endosperm both to enable systems approaches to solve agricultural problems and to replicate this cellular program in diverse species. The projects Dr. Settles has led seek to improve corn genetics, breeding technologies, and identify economically valuable traits for future improvement. Major goals of the research program he initiated here at UF are: to identify germplasm sources that have high tolerance for being planted in cold soils, to better understand starch synthesis and sugar accumulation in the endosperm, to develop near infrared spectroscopy techniques to predict seed and eating quality, and to develop technologies for doubled haploid breeding. As part of these goals, the lab is exploring the use of photosynthetic microorganisms for synthetic biology of endosperm storage molecule accumulation. His synthetic biology goals serve dual purposes in gaining a better understanding of how endosperm accumulates sugars, starch, protein, and oil as well as potentially developing bioregenerative life support systems for space exploration.

Dr. Settles' ResearchGate.

Since Dr. Settles has accepted his new position at NASA, Dr. Curt Hannah - Emeritus Professor at UF and maize biology expert - has stepped in to assist the remaining lab members in fulfilling their research goals. The lab is no longer recruiting additional students. 

Photo of Anadaisy in UF polo

Anadaisy Aguirre

Anadaisy Aguirre is an undergraduate student at UF working in the Settles’ lab. She is majoring in Biology, with a minor in Innovation. Anadaisy is currently interested in learning more about space biology, and molecular biology techniques used in horticultural research. After graduating from UF, Anadaisy intends to pursue a PhD in a plant biology program, with special focus on astrobiology. Long term, Anadaisy sees herself working with horticulture or floriculture in either a private industry or a governmental agency. However, she is also interested in working with a conservation agency, an environmental consulting firm, a food company, or a botanical garden.

Photo of Gina in front of bushes

Ma Gina Maramara Babb

Dr. Ma Gina Maramara Babb is the USDA-APHIS contact person for the Settles lab. She oversees and manages the Settles’ lab maize field operations, seed analysis laboratory, high throughput seedling imaging platforms, and seed storage cool rooms. This involves handling administrative tasks related to the use of transgenic materials in the Settles Lab and fields, maintaining lab breeding materials, and assisting with many ongoing field projects. These projects involve generating super synthetics, haploid inducers, Shrunken2 (Sh2)-m1 introgressions, Chr2 Cd QTL introgressions, high oil lines, single kernel NIR scanning, emergence assays, ABA tolerance, and maize transgenics.

Gina's LinkedIn.

Gina's C.V.

Photo of Fang Bai in greenhouse

Fang Bai

Dr. Fang Bai has been working on RNA splicing and epigenetic regulation of maize seed development at the University of Florida since 2012. Currently, she is involved in two projects: a sweet corn breeding project and an endosperm proliferation mutants screening project. From 2007-2012, she was a post-doc at the University of California, San Diego studying the inflorescence architecture and sex determination in maize. She received her Ph. D. in Plant Biology in 2007 from University of California, Riverside. 

Fang Bai's ResearchGate.

Photo of Nicole in greenhouse

Nicole Beisel

Nicole Beisel received her Bachelor's degree in Microbiology with a minor in Biochemistry from Texas State University in 2017. Nicole is working as a Research Coordinator for the lab. She is interested in spaceflight biology and plant genetics. 

Nicole Beisel's ResearchGate.

Photo of Dawei

Dawei Dai

Dr. Dawei Dai currently works as a Post Doctoral Associate in the Department of Horticultural Sciences at the University of Florida. He completed his graduate training at Shanghai University in China. Dawei does research in maize (Zea mays) field genetics, molecular biology, cell biology, and analytical investigations of novel sweet corn combinations.

Dawei Dai's ResearchGate.

Photo of Linda in front of young corn plants

Linda Dao

Linda graduated with a B.S. in Biology at UF and is currently a second-year Horticultural Sciences PhD student. She is studying cold tolerance in sweet corn seedling emergence. You can sometimes find her at a local burger joint, practicing yoga on campus, or backpacking on the Appalachian Trail. 

Linda Dao's Website.

Linda Dao's LinkedIn.

Photo of Hope Hersh

Hope Hersh

Hope received a double major in Biochemistry & Molecular Biology and Plant Biology from Michigan State University. Hope is a upper level doctoral candidate in the Plant Molecular and Cellular Biology Program. Her work in maize focuses on creating new shrunken2 alleles and improving heat resistance in field and sweet corn. Hope is also very interested in spaceflight related biology. She is a lead investigator on a project in which she is exposing algae to both lunar and martian levels of ionizing radiation. Hope also leads the Space Bread project which aims to provide fresh bread for astronauts in space through the use of the same equipment she utilizes in her algae experiments! 

Hope's updated CV

Photo of Barbara Muller

 Bárbara S. F. Müller

Dr. Bárbara S. F. Müller’s research interest is centered on genomics, transcriptomics, and population and quantitative genetics to elucidate the genetic basis of complex traits in plants. Dr. Müller is a Postdoctoral Associate in the Settles’ lab, and her current research focuses on maize and algae genetics. Dr. Müller earned her Ph.D. in Molecular Biology from the University of Brasília (UnB, Brazil) and was a Postdoctoral Research Associate in the Institute of Plant Breeding, Genetics & Genomics (IPBGG) at University of Georgia (UGA, USA).

Müller's ORCID.

Müller's ResearchGate.

Müller's Google Scholar.

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Noriko Suzuki

Noriko is a lab technician in the Settle's Lab. 

A photo of Chiwah

Chiwah Tseung

Dr. Chiwah Tseung is Lab Manager for the Settles Lab. 

Jimmy's headshot

Jimmy Van

Jimmy earned his B.S. degree in Environmental Science from the University of Florida. He has interests in climate science and biofuels, such as ethanol derived from corn. He is also interested in genetics. His current work interests include learning processes such as gel electrophoresis and polymerase chain reaction. Jimmy is considering applying to the Ph.D. programs at UF, Stanford, and MIT.                                                                 

Photo of Tianxiao outside

Tianxiao Yang

Tianxiao received his Masters in Science and Bachelors in Science from Henan Agricultural University in Zhengzhou, China. He is a first-year Plant Molecular and Cellular Biology Ph.D. student in the Settles Lab  Currently, Tianxiao aims to understand the molecular mechanism of endosperm imprinting in maize, using a parent-of-origin-effect mutant.  

Previous Lab Members

Name
Role in Lab
Current Status/ Location
Jeff Gustin
Research Assistant Professor
Geneticist at US Department of Agriculture (USDA) Agricultural Research Service (ARS)
John Williams
Lab technician
--
John Baier
Biological Scientist III
Retired
Romain Fouquet
Post-Doctoral Associate
Trait Discovery Scientist for Monsanto (Pau, France)
Gertraud Spielbauer
Post-Doctoral Associate
Scientific Evaluator for Taxation and Customs Union (München, Germany)
Tesfaye Baye Mersha
Post-Doctoral Associate
Assistant Professor of Statistical Genomics (University of Cincinnati)
Janaki Mudunkothge
Post-Doctoral Associate
--
Madasamy Parani
Post-Doctoral Associate
Professor and Head of Department for the Department of Genetic Engineering at SRM University (Tamil Nadu, India)
Timothy Porch
Post-Doctoral Associate
Research Scientist for USDA-ARS Tropical Agricultural Research Station (Mayaguez, Puerto Rico)
Camilla Ribeiro
Doctoral Student
University of Florida
Junya Zhang
Doctoral Student/ Post-Doc
Post-Doctoral Associate at Washington University, St. Lois
Christine Gault
Doctoral Student
Post-Doctoral Associate in Maize and Tripsacum Genetics, Cornell University
Federico Martin
Doctoral Student
Post-Doctoral Associate at Colorado State University
Diego Fajardo
Doctoral Student
Biological Scientist III at Shannon E. Boye Laboratory, Department of Pediatrics in the College of Medicine at University of Florida
Li Li
Master’s Student
--
 

Previous Visiting Scientists

Name
Role & Home University
Dates
Zhiyuan Fu
Associate Professor at Key Laboratory of Wheat and Maize Crops, Henan Agricultural University
8/2018-8/2019
Xioajin Zhou
Associate Professor at Biotechnology Research Institute, Chinese Academy of Agricultural Sciences
12/2016-12/2017
Miaoyun Xu
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences
4/2014-3/2015
Antonio Malgiolio
Doctoral Student at University of Milan, Italy
2011
Wellington Gomes
Doctoral Student at Federal University of Vicosa, Brazil
2011-2012